American Politicians And Opioid Stocks Equal Corruption And Death

(THIS ARTICLE IS COURTESY OF EQUITIES.COM NEWS)

 

​Naloxone Stocks: Who’s Really Winning the Battle Against the Opioid Epidemic?

Henry Truc  | 

Despite wider recognition in recent years of the pervasive opioid epidemic spreading throughout the US, death rates from prescription drug overdoses have continued to skyrocket. Deaths from heroin and opioid painkiller overdoses have more than quadrupled since the start of the millennium and have now surpassed car accidents as the leading cause of accidental deaths in the country. But while admission of a problem is the first step to recovery, identifying and eventually addressing the numerous factors that led to this point will still take years, if not decades, to repair.

Until then, over 125 people are dying each day on average from drug overdoses—well over half of which are from heroin or prescription painkillers like hydrocodone (e.g., Vicodin), oxycodone (e.g., OxyContin, Percocet), morphine (e.g., Kadian, Avinza), codeine, and related drugs. It’s a frightening statistic, and government and health officials around the country have been desperate for something to help them get a handle on the spiraling epidemic. That’s a primary reason for the exploding interest in Naloxone, a life-saving drug that counters opioid effects, including reversing overdoses.

On Monday, Walgreens (WBA) announced that it is making Naloxone, a medication that counters opioid overdose, available in more than 110 of its pharmacies in Alabama without a prescription. The rollout is part of Walgreens’ nationwide plan announced in February to make Naloxone available without a prescription in 35 states and Washington DC. Thus far, New York, Rhode Island, Massachusetts, Indiana, Ohio, Pennsylvania and now Alabama have expanded access to the medication. The program is expected to expand Naloxone availability to 5,800 of Walgreens’ 8,500 locations in the US. CVS (CVS) is also rolling out the drug in 14 states as well.

Pennsylvania, meanwhile, also made news recently when health officials introduced a plan to make Naloxone available at all of its high schools. Drug overdoses accounted for 2,000 deaths in the state last year.

The Race to Make Naloxone a Household Drug

Approved by the FDA in 1971, Naloxone is a generic drug that has actually been around for decades. It was used primarily in hospitals and by paramedics, but in recent years, higher demand for first responders and police officers to have the medication kits on hand has driven up the price of the drugfrom only $1 as recently as a decade ago to over $40 today. While the drug has been increasingly heralded by government and health officials as a biotech wonder drug and critical weapon against the growing epidemic in recent years, the outcry over aggressive price hikes has also been getting louder.



Now, with Naloxone becoming readily available over the counter across the US, demand is only going to increase, especially if consumers are being told they need to keep the medication handy in case of an emergency situation, however improbable that may be.

In November 2015, Adapt Pharma Ltd.’s NARCAN Nasal Spray formulation was approved by the FDA, opening the naloxone market up to the OTC market. The NARCAN Nasal Spray is based on the intranasal opioid antagonist platform technology of Opiant Pharmaceuticals, Inc. (OPNT)—which changed its name in February from Lightlake Therapeutics. In March, Opiant received a $2.5 million milestone payment from Adapt following the first commercial sale of the NARCAN Nasal Spray. Under the licensing deal, which was signed in December 2014, Opiant could receive total potential milestone payments of more than $55 million, and up to double-digit percentage royalties on net sales.

Suddenly, a Rapidly Crowding Market

But Adapt isn’t the only game in town. Hospira (a subsidiary of Pfizer [PFE]) and Amphastar Pharmaceuticals (AMPH) have been the leading providers of injectable naloxone for years, and the principle drivers of the price hikes.

Amphastar has also been selling an intranasal application, which administers its injectable formulation with an atomizer, for some time now. The company has also said it’s working on a naloxone nasal spray. In 2015, naloxone sales accounted for $38.6 million of the company’s $251.5 million in annual revenue, but was its fastest-growing segment with increased volume and higher average prices.

Another competitor, Kaleo Pharmaceuticals, is selling a naloxone auto-injector called Evzio at a considerably higher price of about $700-$800 per dose. Biotech giant Mylan (MYL) also sells a naloxone injectable formulation after obtaining FDA approval in 2014. Embattled INSYS Therapeutics (INSY)—which has seen its stock price collapse in the past year as a result of backlash to its opioid-based painkiller Subsys Fentanyl—also got its naloxone candidate designated on the fast track by the FDA.

More Price Hikes to Come?

For all the life-saving benefits of naloxone, it’s important to remember that, at best, it’s just a stop-gap solution to treat a symptom—albeit an incredibly significant one—rather than a cure for a condition. Critics of wider naloxone availability point to the possibility that expanded access creates a moral hazard and doesn’t address the crux of the problem—which is the actual opioid addiction. But again, that is a systemic problem that will take years, if not decades, to resolve.

In the meantime, pharma companies know they have yet another life-saving drug in their pipeline and the means to leverage it for more dollars from willing buyers. But one of the key advantages that companies like Hospira and Amphastar had a few years ago was that they owned an essential monopoly on the naloxone market—largely due to competitors leaving the space over time and thus reducing price competition. But as the field continues to get more crowded over time again, the window to maximize profits could be beginning to close. It’s just a matter of supply and demand at this point.

DISCLOSUREThe views and opinions expressed in this article are those of the authors, and do not represent the views of equities.com. Readers should not consider statements made by the author as formal recommendations and should consult their financial advisor before making any investment decisions. To read our full disclosure, please go to: http://www.equities.com/disclaimer

Companies

Symbol Name Price Change % Volume
INSY Insys Therapeutics Inc. 7.40 -0.21 -2.76 317,788  Trade
PFE Pfizer Inc. 36.16 -0.11 -0.30 12,238,708  Trade
WBA Walgreens Boots Alliance Inc. 69.28 1.99 2.96 13,476,825  Trade
AMPH Amphastar Pharmaceuticals Inc. 18.19 -0.06 -0.33 78,906  Trade
MYL Mylan N.V. 38.78 -0.14 -0.36 3,030,309  Trade
OPNT OPNET TECHNOLOGIES INC 29.33 0.33 1.12 32,045  Trade

Comments

Governments If You Really Want To Stop Heroin And Opiate Deaths: Then Legalize Marijuana Now

 

I know that there are folks who have read this title and had all kinds of different emotions flow over them and this is understandable. Here in the U.S. big government and big media have a long history of distorting what the truth is concerning marijuana. I credit the mainstream media for simply being stupid and running with whatever the federal government tells them. Big government and by big government I do mean from city, county, state and federal organizations where some are just ignorant, some are corrupt, and some are both concerning the concept of making marijuana legal again for the people to consume like a lot of folks do wine, champagne or beer. Yet it has been in the interest of different governments, police agencies and some big lobbyist groups to keep marijuana illegal for their own financial profits they make from such an hypocritical system. Now I know that a lot of folks who read my articles are a bit confused about my stance on legalizing marijuana or even mad at me because the underlying theme on by blog is Christianity. This is true, yet what is the title of my blog site? It is Truth Troubles isn’t it? In my belief system Christianity is Truth so truth troubles is about speaking the truth even if it is something that goes against what we hear in Church, the media, or from the government. Throughout Scripture in the Old Testament and the New Testament we are told many times that wine and alcohol were given to us humans for our enjoyment, but we are also told not to be gluttonous when we are partaking of them. God also gave mankind plants like Mandrake for our enjoyment. Remember back to the founding Fathers of Israel, Abraham, Isaac and Jacob, remember Isaac had two wives of which his favorite was Rebecka and how she gave his other wife some of her Mandrake so that she could get to sleep with Isaac that night even though it wasn’t her turn? Mandrake does the same type of things as marijuana does as far as giving a person a ‘buzz’, if it is okay for the founding Fathers of Israel and their wives, you get the picture? Even here in America our own Founding Fathers like George Washington, Thomas Jefferson and Ben Franklin grew pot in their own personal gardens. Think about this for a moment, the night that Rebecca got to sleep with Isaac when it wasn’t her turn is the night she was impregnated with Jacob, the man who’s 12 sons the 12 tribes of Israel are named after. Remember that the first reported miracle of Jesus was turning water into wine and no it was obviously not ‘grape juice’ or the ‘governor’ of the party would not have referred to it as the best. As Christians we all have to quit acting like hypocrites on these issues.

 

I was born in 1956 and the first time I ever tried ‘pot’ was when I was 17, it was just some cheap homegrown that was so weak that it didn’t do anything to me. I was probably about 22 or 23 before I smoked marijuana again yet I was around lots of folks who did smoke it literally every day  when they could afford to buy it. In fact just about everyone I knew smoked it at least every once in a while. Most all of these people that I have known throughout the years didn’t even drink alcohol and if they did it was just an occasional beer. None of these people used any of the ‘hard drugs’ like Crack, Heroin or were users of pills. A lot of the people that I have known throughout my life who were able to keep smoking a little ‘pot’ in the evenings and on weekends at their homes never ever did go onto other type of drugs, not even alcohol. The Government and the big Media like to call marijuana a “gateway” drug, saying that when most people start off smoking pot that they progress into the harder drugs, the way in which they frame their argument is a lie, period.

 

The people that I know who have gone onto harder drugs like Heroin and opioid pills is because those drugs tend to flush out of a person’s system in about 72 hours. People have always throughout human history have wanted to have something they can have for relaxation and for a gentle ‘buzz’. When the U.S. Government decided to act stupid and classify marijuana a level one drug like Heroin and encouraged all businesses to start doing pre-employment and random drug screens on their workers almost all of the people that I know quit smoking marijuana because it stays in a person’s system for at least 30 days and they could not afford to lose their jobs. Most all of the people that I know who did quit smoking pot started drinking alcohol in place of it. Unfortunately there are millions of people who instead of smoking marijuana did turn to the real hard drugs. So, in a since, yes marijuana did become a ‘gateway’ drug in that people quit using it because it stayed in their systems so long that millions of people who would have never gone onto drugs other than marijuana have done so and the result is thousands of people are dying every year because of these hard drugs. Marijuana has never ever even killed one person! Now let’s look at states like Colorado since they made marijuana legal for adults, checkout the amount of overdose deaths from before they made marijuana legal and then sense they made it legal. I am no computer whiz to say the least so I will leave your investigations up to you, but I do ask you to check out the stats. I remember reading a Colorado newspaper online about two or three months ago concerning this issue and the results were rather stark, the amount of overdose deaths are way down as they are in Washington State.

 

Truth is that all this “war on marijuana” has done is to put a lot of money into drug cartels pockets and cost hundreds of thousands of people their lives. Our Nation’s policies are idiotic, un-Christian and un-Jewish as well as being immoral. If our government was really interested in cutting down on overdose deaths from these hard drugs thus cutting down on the amount of these drugs coming into our country and giving drug cartels billions of dollars each year then they would create a system where pot is treated like beer or wine. Marijuana should be made to be cheaper than Heroin, Morphine or Crack. States who have actually done what the people of their states have voted for (when they have been allowed to vote on the issue, places like here in Kentucky refuse to allow a vote on it) the States have benefited with hundreds of millions in new tax revenue along with creating thousands of new jobs to help spur their economies. When our Government decided to create this “war on drugs” they through their own ignorance and hypocrisy took a benign medically helpful God-given Erb away from the people and have been the driving force behind the reason that millions of people worldwide are now dead. If our Nation was actually serious about stopping thousands of people from dying each year to drug overdoses then they need to get a clue and make marijuana totally legal in Our Country just like beer and wine is.

Heroine Overdoses In America An Epidemic: Many Young Children With Dead Parents

(THIS ARTICLE IS COURTESY OF THE WASHINGTON POST)

A 7-year-old told her bus driver she couldn’t wake her parents. Police found them dead at home.

October 5 at 6:46 AM

7-year-old told her bus driver she couldn’t wake her parents. Police found them dead at home.

Two parents were found dead of suspected drug overdoses after their 7-year-old child told her bus driver she couldn’t wake them, according to authorities in McKeesport, Pa. (WPXI)

For more than a day, the 7-year-old girl had been trying to wake her parents.

Dutifully, she got dressed in their apartment outside Pittsburgh on Monday morning and went to school, keeping her worries to herself. But on the bus ride home, McKeesport, Pa., police say, she told the driver she’d been unable to rouse the adults in her house.

Inside the home, authorities found the bodies of Christopher Dilly, 26, and Jessica Lally, 25, dead of suspected drug overdoses, according to police.

Also inside the home were three other children — ages 5 years, 3 years and 9 months.

The children were unharmed but still taken to a hospital to be checked out, then placed with the county’s department of children, youth and families.

The case cast a light on Allegheny County’s epidemic of drug overdoses — and their impact on families.

“There is an opioid overdose epidemic in the U.S., and Allegheny County is not immune,” county health officials said in a recent report.

There were 422 opioid-overdose deaths in Allegheny County last year, according to the report — the largest death toll in county history. “And the upward trend continues.”

The report noted that Allegheny County, which includes McKeesport and the city of Pittsburgh, “has experienced fatal overdose rates higher than those seen throughout Pennsylvania and many other states” during the past decade.

Illustrating their point, authorities told NBC affiliate WPXI that the double overdose at the 7-year-old’s home was the second they had responded to on that block in less than a day.

Speaking before the state legislature last week in Harrisburg, Gov. Tom Wolf (D) told lawmakers that the opioid epidemic facing Pennsylvania is “a public health crisis, the likes of which we have not before seen. Every day, we lose 10 Pennsylvanians to the disease of addiction. This disease does not have compassion, or show regard for status, gender, race or borders.

“It affects each and every Pennsylvanian, and threatens entire communities throughout our commonwealth. The disease of addiction has taken thousands of our friends and family members. In the past year alone we lost over 3,500 Pennsylvanians — a thousand more lives taken than the year before.”

Wolf added that “addiction too often is an invisible problem. … But in Pennsylvania the problem is visible: In the lives lost. The families broken. The communities shaken.”

Nationwide, opioids such as heroin and prescription pain relievers killed more than 28,000 people in 2014, more than any year on record, according to the Centers for Disease Control and Prevention. At least half of all opioid overdose deaths involved a prescription drug, the CDC said, adding that the number of overdose deaths involving opioids has nearly quadrupled nationwide since 1999.

Behind the grim statistics are haunting scenes of overdose victims — and the children affected by their parents’ addictions.

Last month, a Family Dollar store employee in Massachusetts recorded a toddler in pink pajamas crying and pulling on her unconscious mother, who had overdosed and collapsed in the toy aisle.

The mother, who survived, was charged with child endangerment. Her daughter was placed under the care of child protective services.

Toddler tries desperately to wake mother who collapsed in store

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The woman collapsed in an apparent overdose at a Family Dollar store in Lawrence, Mass., is expected to be charged with child endangerment. (Editor’s note: This video may be disturbing to viewers.) (Lawrence Police Department)

Also last month, authorities in the Ohio city of East Liverpool released a photo of a man and a woman overdosing inside a vehicle that police said had been moving erratically. The driver was barely conscious; the passenger was turning blue. In the back: a 4-year-old boy restrained in a car seat.

Someone at the scene snapped a photo of the gruesome scene and the city posted it on its Facebook page “to show the other side of this horrible drug.”

And a photo of a Birmingham, Ala., police officer comforting a 1-month-old girl in a tiny purple gingham dress raced around the Internet after her father died of an apparent drug overdose and her mother was found near death.

The officer in the picture, Michelle Burton, told The Washington Post about the moment that night that saddened her the most. The couple’s 7-year-old daughter asked the officer to sign her homework so she could turn it in at school the next day.

“That broke my heart,” Burton said. “She said, ‘I did my work.’ She pulled it out and showed it to us. It was math homework — ‘Which number is greater? Which number is odd or even?’ … I told her, ‘Sweetie, you probably won’t have to go to school tomorrow. … But where you’re going is going to have everything you need.’ ”

She added: “It was horrible. It was a very sad situation.”

In Pennsylvania’s Lycoming County, coroner Charles Kiessling started recording the manner-of-death classification in most drug-overdose deaths as homicides earlier this year.

A lot was already being done to curb heroin use in his community, Kiessling told The Post — but using an accidental-death classification for an overdose felt as if he was “sweeping the problem under the carpet, to a certain extent.”

“They’re not accidental deaths,” Kiessling said. “They’re homicides. Drug dealers are murderers. They need to be prosecuted as murderers.”

Homicide is defined as the death of an individual at the hands of another, Kiessling said; when he thought about drug deaths, the victims were dying at the hands of a dealer or supplier.

“You’re killing people if you’re selling drugs,” he said.

In March, at the National Prescription Drug Abuse and Heroin Summit, President Obama called opioid abuse and overdose deaths “heartbreaking,” adding: “I think the public doesn’t fully appreciate yet the scope of the problem.”

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