How the humble cabbage can stop cancers

(THIS ARTICLE IS COURTESY OF THE BBC)

 

How the humble cabbage can stop cancers

CabbageImage copyright GETTY IMAGES

Scientists say they have discovered why some vegetables – including cabbage, broccoli and kale – can reduce the risk of bowel cancers.

That cruciferous veg is good for the gut has never been in doubt but a detailed explanation has been elusive.

The team at the Francis Crick Institute found anti-cancer chemicals were produced as the vegetables were digested.

Cancer Research UK said there were plenty of reasons to eat more veg.

The work focused on how vegetables alter the lining of the intestines, by studying mice and miniature bowels growing in the lab.

Like the skin, the surface of the bowels is constantly being regenerated in a process that takes four to five days.

But this constant renewal needs to be tightly controlled, otherwise it could lead to cancer or gut inflammation.

And the work, published in the journal Immunity, showed chemicals in cruciferous vegetables were vital.

From kitchen to cancer prevention?

The researchers investigated a chemical called indole-3-carbinol, which is produced by chewing such vegetables.

“Make sure they’re not overcooked, no soggy broccoli,” said researcher Dr Gitta Stockinger.

The chemical is modified by stomach acid as it continues its journey through the digestive system.

In the lower bowel, it can change the behaviour of stem cells, which regenerate the bowel lining, and of immune cells that control inflammation.

The study showed diets high in indole-3-carbinol protected the mice from cancer, even those whose genes put them at very high risk of the disease.

Without the protective diet, the gut cells divided uncontrollably.

Dr Stockinger added: “Even when the mice started developing tumours and we switched them to the appropriate diet, it halted tumour progression.”

Presentational white space

Signs of bowel cancer include persistent:

  • blood in the stools
  • changes in bowel habits, such as going to the toilet more often
  • tummy pain, bloating or discomfort
Presentational white space

Dr Stockinger said the findings were a “cause for optimism”.

She has reduced the amount of meat she eats and now consumes a lot more vegetables.

She told the BBC: “A lot of dietary advice we’re getting changes periodically – it is very confusing and not clear cut what the causes and consequences are.

“Just telling me it’s good for me without a reason will not make me eat it.

“With this study, we have the molecular mechanisms about how this system works.”

Prof Tim Key, from Cancer Research UK, said: “This study in mice suggests that it’s not just the fibre contained in vegetables like broccoli and cabbage that help reduce the risk of bowel cancer, but also molecules found in these vegetables too.

“Further studies will help find out whether the molecules in these vegetables have the same effect in people, but in the meantime there are already plenty of good reasons to eat more vegetables.”

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Shanghai China: Focus on cancer prevention

(THIS ARTICLE IS COURTESY OF SHANGHAI CHINA’S ‘SHIELD’ NEWS)

 

Focus on cancer prevention

Cancer morbidity in Shanghai has risen 141 percent in the past four decades, according to the latest data released by local health authorities.

But the rate of deaths among cancer patients dropped by 42 percent in this period due to better screening, registration and monitoring.

This week is the city’s Cancer Prevention and Treatment Week with various events promoting cancer prevention.

An opening ceremony was held on Sunday in Changning District which included a walking race.

Data shows that almost 30 percent of local adults do not engage in physical activities and more than 30 percent are overweight. Nearly 10 percent suffer obesity.

Research shows that 40 percent of the causes of cancer in China are bad habits such as lack of exercise, poor diet, smoking and drinking.

Residents who want to know more about cancer and related activities can find information on the WeChat accounts of the local heath commission and center for disease control and prevention.

By 2015, cancer was the second major cause of death in Shanghai.

More than 70,000 people in Shanghai were diagnosed with cancer and nearly 40,000 died as a result in 2015.

Giving cancer patients hope is as valuable as giving them medicine

(THIS ARTICLE IS COURTESY OF THE TIMES OF ISRAEL)

 

Giving cancer patients hope is as valuable as giving them medicine

Israeli cancer patients rely on ICSN’s volunteers and services to help them cope, fight, and recover

Families grappling with the double pressures of watching their children suffer through cancer while simultaneously having earn a living benefit most from ICSN's services, such as transport and financial assistance.

Families grappling with the double pressures of watching their children suffer through cancer while simultaneously having earn a living benefit most from ICSN’s services, such as transport and financial assistance.

To recover from cancer, having the best doctors, treatment, or medication is not enough. Without hope and personal connection, the prognosis for cancer patients is decidedly poorer. This is exactly why Israel Cancer Support Network (ICSN) offers cancer patients and their families the warmth they need to survive emotionally and the firm support they need to meet the challenges of suffering through painful cancer treatments. 

The emotional, physical, and fiscal strain of treating cancer, from arranging doctors’ appointments to meeting personal expenses and trying to maintain a “normal” family life, are hurdles that many have a tremendously difficult time overcoming.

In less than a decade, ICSN has helped over 11,000 families dealing with cancer, giving 50,000 car rides to cancer patients in need of transportation to the hospital and back. That comes out to 150 trips each day. ICSN uses a network of volunteers to create a community of support throughout Israel. Over 2,000 multilingual volunteers from the Jerusalem metro area and further away take time out of their busy lives to transport cancer-stricken children and adults to and from the hospital, around the clock year-round.

But these services represent only a fraction of what ICSN does.

ICSN sets up fully stocked, 24/7 coffee stations in cancer wards so that patients and families can savor a hot drink at any hour of the day. In its 15-year history, the organization has served over a million cups of coffee to cancer patients. ICSN also assists patients with the herculean task of gaining access to top doctors with long waiting lists for appointments.

The bottom line is that ICSN’s services are integral to the recovery of those who use them.

Many families suffer extreme difficulties as a result of cancer treatment and the financial damage caused by months of treatments can be crippling. Patients often lose their jobs due to the inability to work while parents miss countless hours of work accompanying their children to treatments. ICSN eases the burden by offering cash stipends and gift certificates to cover the cost of household help, including shoes, clothing, basic food items and life-saving drugs.

But beyond the financial, physical, and logistical help they provide, ICSN most importantly furnishes cancer patients with hope.

“A smiling volunteer driver picking you up in the middle of the night with his car to take you to the hospital is just as valuable as the cancer treatment itself,” said Shlomi, a recipient of ICSN’s services.

Personal outreach has a distinct therapeutic effect, according to Professor Dina Ben-Yehuda, director of Hematology at Hadassah Ein-Kerem and professor of Hematology at Hebrew University’s Faculty of Medicine. “When you battle a disease like cancer, the supporters are just as important as the fighters.”

During the High Holidays, ICSN goes the extra mile to give cancer patients in need the serene conditions in which to celebrate and usher in the new year.

ICSN functions entirely through donations with no external support.

Learn more about how you can help cure cancer.

Charles Krauthammer ‘Only A Few Weeks Left To Live’

(THIS ARTICLE IS COURTESY OF THE HUFFINGTON POST)

 

Charles Krauthammer Pens Final Column: ‘Only A Few Weeks Left To Live’

“This is the final verdict. My fight is over,” the Washington Post columnist wrote.
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In his final column for The Washington Post, Pulitzer Prize-winning columnist and Fox News pundit Charles Krauthammer announced he has only weeks to live.

Krauthammer explained he’s spent most of the last year recovering from surgery to remove a cancerous tumor in his abdomen.

Although the operation was initially thought to have been successful, Krauthammer said he’s been fighting “a cascade of secondary complications” ever since.

FNC

“It was a long and hard fight with many setbacks, but I was steadily, if slowly, overcoming each obstacle along the way and gradually making my way back to health,” he wrote.

However, the cancer returned and is spreading rapidly.

“My doctors tell me their best estimate is that I have only a few weeks left to live. This is the final verdict. My fight is over,” he wrote.

Krauthammer said he is ”grateful to have played a small role in the conversations that have helped guide this extraordinary nation’s destiny.”

He added:

I leave this life with no regrets. It was a wonderful life — full and complete with the great loves and great endeavors that make it worth living. I am sad to leave, but I leave with the knowledge that I lived the life that I intended.

In a separate column, the Post’s editorial staff honored Krauthammer, saying, “His unsparing judgments were cheered by some readers while angering others. But few could disagree that he wrote a column of breathtaking range and intelligence and integrity.”

Krauthammer graduated from Harvard Medical School in 1975 even after suffering a diving accident as a freshmen that left him paralyzed for the rest of his life, according to Fox News.

He switched to journalism in the early 1980s after spending some time writing speeches for Walter Mondale.

Krauthammer became a columnist for The Washington Post in 1985 and won a Pulitzer Prize two years later.

Rupert Murdoch, whose media empire includes Fox News, responded to Krauthammer’s column with a tribute tweet, saying the pundit’s “always principled stand on the most important issues of our time has been a guiding star in an often turbulent world.”

Fox News

@FoxNews

A statement from Rupert Murdoch on Charles Krauthammer’s cancer diagnosis. https://fxn.ws/2xVqH3d 

 

Groundbreaking Treatment Cures Woman’s Advanced Breast Cancer in World First

(THIS ARTICLE IS COURTESY OF THE GUARDIAN)

 

Groundbreaking Treatment Cures Woman’s Advanced Breast Cancer in World First

A Florida woman is still alive thanks to a unique style of immunotherapy in treating her aggressive breast cancer.

Doctors and cancer patients around the world are taking note of an incredible piece of news. A new therapy has reportedly cured a woman diagnosed with advanced breast cancer which had spread throughout her body.

This marks the first time that a woman with advanced, late-stage breast cancer has successfully been treated with immunotherapy. The team of doctors used patient Judy Perkins’s own immune cells to combat the disease.

Perkins was just 49 years old when the engineer discovered she’d been picked for a new therapy. She’d already undergone chemo treatments which continued to fail her. At best, Perkins had three years left to live.

Doctors from the US National Cancer Institute located in Maryland suggested the immunotherapy. They called her response to the treatment “remarkable.”

“My condition deteriorated a lot towards the end, and I had a tumour pressing on a nerve, which meant I spent my time trying not to move at all to avoid pain shooting down my arm. I had given up fighting,” Perkins said in an interview with The Guardian. “After the treatment dissolved most of my tumours, I was able to go for a 40-mile hike.”

Laszlo Radvanyi serves as a scientific director at the Ontario Institute for Cancer Research. Like many keeping up with this news, Radvanyi was not involved in treating Perkins. However, he’s certainly taking notice — calling the treatment “an unprecedented response in such advanced breast cancer.”

“We are now at the cusp of a major revolution in finally realising the elusive goal of being able to target the plethora of mutations in cancer through immunotherapy.”

“We are now at the cusp of a major revolution in finally realising the elusive goal of being able to target the plethora of mutations in cancer through immunotherapy,” Radvanyi said.

Doctors now hope for a major revolution in treatment opportunities available for patients. Some research teams are already developing massive clinical trials to determine just how effective immunotherapy could be for certain patients.

Simon Vincent, director of research at Breast Cancer Now, told interviewers: “This is a remarkable and extremely promising result, but we need to see this effect repeated in other patients before giving hope of a new immunotherapy for incurable metastatic breast cancer.

“Metastatic breast cancer remains incurable, and if we are to finally stop women dying we urgently need to find new ways to target and stop the spread of the disease. We are thrilled by this early finding, but we must remember that this type of immunotherapy remains an experimental approach that has a long way to go before it might be routinely available to patients.”

The process of immunotherapy takes biopsies of the primary tumor and its metastases to determine any mutations specific to a patient’s cancer. Those immune cells that made it through tumor tissue then get cultivated into billions of immune cells in a lab. The tumor tissue itself goes through a bit of gene sequencing so researchers know the main mutations of the tissue. The immune cells being grown then get analyzed to see which ones can target cancer specifically. Those immune cells are the ones that get put back into a patient in order to kill the cancer cells.

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Perkins had over 80 billion immune cells put into her body. After 42 weeks of treatment, Perkins was declared free of cancer.

She’s been free of cancer ever since.

“It feels miraculous, and I am beyond amazed that I have now been free of cancer for two years,” Perkins said.

“I had resigned my job and was planning on dying. I had a bucket-list of things I needed to do before the end, like going to the Grand Canyon,” she added. “Now, I have gone back to normal everyday life.”

Via: The Guardian

New nano treatment gives cancer patients fresh hope

(THIS ARTICLE IS COURTESY OF SHANGHAI CHINA’S NEWS AGENCY ‘SHINE’)

 

New nano treatment gives cancer patients fresh hope

The world’s first surgery using NanoGun technology — jointly developed by Chinese and French scientists — was performed on a lung cancer patient in Shanghai yesterday.

The new minimally invasive treatment, which can be used on patients deemed no longer healthy enough for chemotherapy, injects the radioactive element rhenium-188 covered with nano-particles, including nitroimidazole — an organic matter.

While engulfing the nitroimidazole, the cancer cells also take in the rhenium, which eventually kills the tumor.

The patient, 71, was in the terminal stage of lung cancer and was too ill for further chemotherapy.

“It usually takes three days for the rhenium to kill the cancer cells,” said Gao Yong, the doctor in charge of the operation at Shanghai East Hospital. “There won’t be any side effects (from the rhenium) as the element will lose its radioactivity after three days.”

NanoGun is a Shanghai-based technology developed from scratch. It won China’s top innovation award in 2016.

Yang Guanghua, one of the scientists who helped develop the technology, said that although rhenium had long been ideal to treat cancer, there had been no ideal medium for delivery. It often diffused throughout the body and was hard to be absorbed by the irregular shaped cancer cells.

It took Yang and his colleges almost 10 years to find the right coating material, nitroimidazole, which matches perfectly with rhenium to make sure it directly reaches the nidus, or “nest”, of the cancer.

“Diffusion of the element (rhenium) hindered the effectiveness of the treatment in the past,” said Dr. Sadeg Nouredine, one of the French scientists working with Yang.

The surgery, approved by the hospital’s ethics committee as part of the treatment’s clinical trial, was free.

“We are working on the next stage of the technology in the lab,” said Yang. “So that it can hit multiple niduses simultaneously.”

If the trial succeeds the treatment will be available by 2020, by which time Shanghai will have built a pharmaceutical factory and hospital in Songjiang District to provide rhenium.

(Humor Poem) Queen Piggy

QUEEN PIGGY

 

Queen Piggy we inherited her when cancer

Took her mommy from this earthly world

She was a mere six months old

When she came prancing and dancing

Into our family’s little fold

 

 

She was so cute you just had to hold and love her

For wherever she was, she always stole the show

Everyone who ever cast their eyes upon her

Would soon lose their heart to this hairy little girl

For 18 wonderful years she ruled our little home

 

 

To her, every hand she met was a new friend

For everyone always wanted to pet and hold her

So cute partly because of her snarly little grin

You see, Queen Piggy was a Pekingese puppy

With smashed snout, hairy toes and toothy smile

 

 

Everyone that she met was now her newest best friend

We loved this little girl as to our home, light she did bring

But now it’s the Angels turn to smile with Queen Piggy

Flying around Heaven tucked up underneath their wings

Here on earth we will always miss her and her sweet love

 

 

All the smiles she brought we will always miss her

But who am I or we to complain of missing her love

For last night in my dreams the scene I did see her

I saw Piggy fast asleep being petted by our Savior

There in Heaven upon the Good Lord’s knee

Thousands of strangers gave a sick child an early Christmas. Days before Thanksgiving, he died.

(THIS ARTICLE IS COURTESY OF THE WASHINGTON POST)

 

Thousands of strangers gave a sick child an early Christmas. Days before Thanksgiving, he died.

 November 20 at 2:28 PM

Jacob Thompson, 9, died Sunday after fighting a rare cancer for four years. (Family photo)

Jacob Thompson spent nearly half of his short life battling cancer.

The 9-year-old boy, who loved penguins, died Sunday, four years after he was diagnosed with Stage 4 neuroblastoma, a rare cancer that affects mostly young children.

As his family had expected, Thompson didn’t live long enough for Christmas, a holiday he loves. But shortly before his death, countless friends, family members and complete strangers inspired by the terminally ill boy’s story brought an early Christmas to him. They decorated his hospital room with a tree, requested a special visit from Santa Claus, and sent him gifts and dozens of homemade holiday cards.

Jacob and his family celebrated Christmas on Nov. 12. He died a week later.

“Each and every person who sent Jacob a Christmas card, a gift, a Facebook message or video, or a prayer made a difference in the final days of his life,” his family, from Saco, Maine, wrote on a Facebook page they used to chronicle his journey. “You brought Jacob joy, and you brought us all optimism for the future. Thank you for taking the time, and taking an interest in our sweet boy’s journey. Sadly, there are many others like him that we hope you will continue to help.”

Jacob was admitted to the hospital “for the last time” Oct. 11, his mother, Michelle Thompson Simard, wrote on a GoFundMe page. The cancer had spread to his skull and to several bones in his inner ear. His hip was so covered with tumors that it looked like lace, Thompson Simard wrote. Chemotherapy and radiation had offered little signs of hope.

The boy’s family was “told that we should be spending as much time as possible with him and we should start making arrangements for his passing,” Thompson Simard wrote, adding later, “No one thinks about having to do this type of planning for their child and because of that we did not nor do not have life insurance on him.”

The GoFundMe campaign has raised nearly $160,000 as of Monday to pay for Jacob’s funeral.

Thompson Simard documented the response from people who sent Christmas cards and toys to make the early holiday memorable for Jacob. On Nov. 1, she posted a picture of Jacob with the first card he received. It featured a penguin, which his family, from Saco, Maine, says is his favorite animal.

For the next several days, Jacob was showered with presents. Pictures his mother shared on social media showed boxes of toys, games, books, cards and, of course, more penguins — including penguin socks.

He even received a video greeting from actor Rob Lowe and the cast of “Code Black.”

Merry Christmas, Jacob! http://dlvr.it/Pyx3zQ  Please send cards:
Jacob Thompson
Maine Medical Center
22 Bramhall St
Portland, ME 04102

Barbara Bush Children’s Hospital in Portland, Maine, where Jacob was being treated, saidthe response was “wonderfully overwhelming” but asked people to not personally deliver cards to the hospital because of safety concerns.

On Thursday, three days before Jacob died, his family shared a picture of him in his hospital bed wearing a blue Superman T-shirt. His dog, Piper, was lying near his feet.

Jacob had just gone through a round of radiation to help him with some pain in his leg, his family wrote.

“Jacob spends most of his time resting, but has had a few good hours to play and open all your cards and gifts,” his family wrote.

In the post announcing Jacob’s death, his family said they hope his story would help raise awareness about neuroblastoma, a rare type of cancerous tumor that affects mostly infants and young children, according to the American Cancer Society. There are about 700 new cases every year in the United States. The majority are diagnosed by age 5.

“We hope that donations will be made, and a cure will be discovered as a result,” Jacob’s family wrote.

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